When signals from nerve fibers reach the brain to be processed, people experience pain. It frequently follows tissue damage and enables the body to respond to and avert damage. Everybody experiences pain differently, and there are many different ways to feel and express pain. In certain situations, this variance may make it difficult to identify and manage pain. Pain can be localized, lasting a short while, or it can spread throughout the body. When certain nerves known as nociceptors identify tissue damage and send information about the damage to the brain via the spinal cord, people experience pain. For instance, contacting a heated surface will trigger an instantaneous muscle contraction by sending a signal through the spinal cord's reflex arc. In order to prevent more damage, this contraction will draw the hand away from the heated surface. This reaction takes place prior to the message reaching the brain. An unpleasant sensation known as pain is experienced by the person upon receiving the pain message.

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